Scorpion (real name: MacDonald "Mac" Gargan) is a Marvel Comics supervillain that most commonly serves as an enemy to Spider-Man and Iron Fist. He later becomes a member of the Thunderbolts, and is later exposed to a Symbiote and becomes the third Venom as well as the first villain to take on the Spider-Man Mantle when being part of the Dark Avengers.
Mac Gargan was a private investigator initially hired by J. Jonah Jameson to find out how Peter Parker is able to obtain incredible pictures of Spider-Man. Gargan's efforts set off Peter's spider-sense and the teen was able to easily evade the detective. Jameson then decided to hire Gargan as the subject of a barely tested process that would endow him with the useful characteristics of a particular animal with the help of Dr. Farley Stillwell. In this case, a scorpion was the base for the purposes of creating a powerful agent capable of defeating Spider-Man. The Scorpion proved to be more than a match for the wall-crawler; defeating him twice, but the mutagenic treatment seriously affected Gargan's mind, driving him insane.
He promptly turned on his benefactor but Spider-Man intervened, and managed to finally defeat the Scorpion in their third battle. Jameson was struck with the irony that he was saved by the man he tried to destroy from the thing he created to destroy him. Since then, the Scorpion became a professional criminal and would return to indulge in his deadly vendetta against Spider-Man and Jameson, only to be defeated again.
He was later hired by a spy ring to follow S.H.I.E.L.D. agent Sharon Carter, but was defeated by Captain America. Scorpion was acquired by Mr. Kline, who created android duplicates of the Scorpion and Mr. Hyde to dispatch against Daredevil. The real Scorpion and Mr. Hyde then launched a campaign of terror against S.H.I.E.L.D. agents, but were defeated by Captain America and the Falcon. After being released from prison for good behavior, the Scorpion resumes his criminal career and encounters and defeats Spider-Man again.
After realizing that the wall-crawler survived the encounter, he receives help from the Jackal who gives him Spider-Man's location. The Scorpion arrives at a hospital room finding Peter Parker and his Aunt May. Not realizing that he had Spider-Man right there, he threatens May and demands to know where Spider-Man is and, after she faints, Scorpion rampages through the hospital. A furious Spider-Man beats the Scorpion and forces him to apologize to May.